Postdoctoral Researcher - Military veterans preferred

Oregon Health & Science University

Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.


Postdoctoral Researcher

US-OR-Portland

Job ID: 2025-34916
Type: Regular Full-Time
# of Openings: 1
Category: Postdoctoral
Portland, OR (Waterfront)

Overview

We are developing an exciting new type of cancer diagnostic test that combines microfluidic and microarray technology to pull cancer-derived nanoparticles straight from plasma. Our long-term goal is to bring nanoparticle-based diagnostics to the clinic for the first time. We are currently hiring for a highly motivated and enthusiastic Postdoctoral Fellow.

We are looking for applicants with expertise in Engineering or Biology to work in some of the following general areas:

• Development of biological particle separation technology using dielectrophoresis – Using microelectrode array chips to recover cancer-derived nanoparticles from circulation (Gustafson, et al. 2021). This novel work will focus on the development and characterization of new nanoparticle recovery technology using dielectrophoretic forces. These forces are created by microelectrode array devices that act on the unique dielectric properties of different particles (Ibsen et al. 2017). This work includes increasing particle collection efficiency, understanding the types of particles that are collected and how they can be separated, and developing an internal standard appropriate for different particle types. This position will utilize the high-end specialized nanofabrication equipment located here at OHSU. This will also involve quantitative fluorescent microscopy imaging, TEM imaging, immunostaining, and particle characterization.
• System automation – continuing development and finalization of an automated system to conduct the dielectrophoresis work. The goal is to automate the dielectrophoresis collection protocol to increase sample analysis throughput. This will involve basic robotics and automation programming in LabView.
• Cancer biomarker panel development – Evaluate the nanoparticle associated biomarkers that are collected for their ability to detect pancreatic cancer from plasma samples. Here the goal is to use the developed dielectrophoresis techniques to collect cancer-derived nanoparticles and evaluate their biomarkers for the ability to detect pancreatic cancer.

• M.D., M.D./Ph.D., or Ph.D.
• Minimum of 3 years as a graduate student
• Specialty: Biomedical Engineering and/or Cancer Biology or related field, Cell Biology,
• Candidates must have experience working in a laboratory environment
• Excellent communication, analytical and organizational skills
• Ability to work independently and as part of a team while being collaborative in resolving problems
• Passion for science and inquiry
• Ability to synthesize one’s own results and others to formulate hypotheses
• Must possess energy and drive to coordinate multiple projects simultaneously
• Ability to use tact and diplomacy to maintain effective working relationships

• Experience with Biotechnology development
  Specialty: Biomedical Engineering, Electrical Engineering, Mechanical Engineering, or Biotechnology development (including Cell Biology or related field)
• Ability to synthesize scientific projects and communicate science to diverse audiences
• Experience with immunostaining and antibody validation
• Experience with data analysis

PI274652596