Research Associate -OR- Senior Research Associate - Military veterans preferred

Research Associate -OR- Senior Research Associate

US-OR-Portland

Requisition ID: 2025-35507
Position Category: Research
Job Type: Research
Position Type: Regular Full-Time
Posting Department: Department of Pediatrics
Posting Salary Range: Commensurate with experience, education and internal equity.
Posting FTE: 1.00
Posting Schedule: In addition to keeping regular work hours, occasional evening and weekend work is also required.
HR Mission: School of Medicine
Drug Testable: No

Department Overview

Sarah Andres' Lab is located within the Department of Pediatrics. The Andres Lab investigates intestinal epithelial differentiation, nutrient handling, and barrier function with a focus on the neonatal inflammatory disease necrotizing enterocolitis (NEC) and the use of human milk extracellular vesicles as a potential therapeutic. By using rare human patient samples, genetic mouse models, and cutting-edge patient-derived organoids, the Andres Lab is at the forefront of research in these fields evidenced by high impact publications and multiple funding sources.

 

We are currently recruiting for a Research Associate or Senior Research Associate depending on qualifications.

Function/Duties of Position

The Research Associate and/or Senior Research Associate is responsible for executing, and overseeing complex organoid experiments and developing functional assays to delineate mechanisms of human milk action on intestinal development and maturation. This involves generating neonatal patient-derived intestinal organoids (enteroids) from surgical tissue samples. Cultivating enteroids requires keen attention to detail and impecable sterile technique. The Senior Research Associate is also responsible for isolating human milk extracellular vesicles via density-gradient ultracentrifugation, quantifying by Nanoparticle Tracking analysis, and running various downstream analyses or experiments including, qPCR, western blotting, immunostaining, imaging and cell uptake studies, microRNA sequencing, proteomics, and oral gavage into rodant models. Experiments are currently focused on nutrient uptake, lipid handing, and metabolism. The ability to manage multiple co-occuring experiments involving enteroids and/or mice is important. In addition to primary project responsibilitoes, this position will assist lab team members with experiments involving neonatal mouse pups, oral gavage, and use of a hypoxic chamber. This also includes intestinal tissue harvest and procesing, enteroid generation and propogation, immune cell isolation and culture, immunostaining and microscopy, and molecular biology.

 

In addition to research skills training, our team prioritizes mentorship and training in career development.

Required Qualifications

Required qualifications for Research Associate:

• Master’s Degree in relevant field AND 3 years of relevant experience OR
• Bachelor’s degree in relevant field AND 5 years of relevant experience.
• 3+ years in a wet bench laboratory

 

Required qualifications for Senior Research Associate:

• PhD in relevant field AND 1 year of relevant experience OR
• Master's Degree in relevant field AND 5 years of relevant experience OR
• Bachelor's Degree in relevant field AND 9 years of relevant experience.
• 5+ years in wet bench laboratory.

 

Job Related Knwoledge, Skills and Abilities:

• Working as part of a team
• Working independently
• Working in dynamic, fast paced environment
• Ability to juggle multiple tasks
• Ability to master detail-oriented techniques and procedures
• Computer skills
• Must have excellent communication, analytical and organizational skills:  both written and verbal
• Experience in cell culture
• Experience in tissue handling
• Experience in molecular biology techniques
• Ability to multi-task
• Flexible
• Strong problem-solving skills

Preferred Qualifications

• Degree in life sciences / biologic sciences
• Laboratory and/or mouse handling
• Laboratory/cell/organoid culture experience
• Cell culture techniques
• Molecular biology skills
• Bioinformatic experience Extracellular vesicle biology
• Metabolism or metabolic studies experience
• Microscopy
• Immunostaining
• Mouse handling experience

Additional Details

***Upload cover letter and resume.  Please be sure to include months and years (MM/YYYY format) to the resume for jobs/experience.

All are welcome
Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.



Equal employment opportunity, including veterans and individuals with disabilities.

PI277282795