Assay Development Consultant - Military veterans preferred

Kikiktagruk Inupiat Corporation, LLC

Assay Development Consultant
Closing Date: Until Filled
Department: Midnight Sun Professional Solutions
Location: USA
Employment Type: Part Time

Title: Assay Development Consultant

Location: Remote

Status: Part-Time

Travel: Yes (anticipated 8 hours annually)

Salary Range: $100 - $150 per hour

Position Summary:

The NIH Blueprint for Neuroscience Research, a consortium of 8 NIH Institutes and Centers that support neuroscience research, established the Blueprint Neurotherapeutics Network (BPN) as a pipeline between the typical endpoint of NIH-funded research and the beginning of industry drug development. The BPN provides neuroscience researchers with funding and access to a full range of industry-style drug development services and expertise. The program is intended for projects requiring medicinal chemistry optimization and contract research organization (CRO) support through Phase I clinical testing. Each project is directed by a Lead Development Team (LDT) composed of the principal investigator (PI), industry consultants hired by NIH, and NIH staff. This team maps out a research strategy, including milestones, and oversees implementation by CROs. Bioactivity and efficacy studies are funded through an award to the PI; other research services can be provided without cost to the PI through NIH contracts.

Assay Development Consultant shall provide this support while serving on NIH BPN, HEAL and other NIH approved Lead Development Teams [LDT]. Lead Development Teams meet for approximately two hours every one to two weeks via teleconference and each LDT project may require between three and ten hours weekly, inclusive of meeting and preparation time. Assay Development Consultant is expected to provide support services in a collaborative way. Lead Development Teams the Assay Development Consultant is assigned to may work on a number of projects in the exploratory through preclinical safety stages. Some projects may proceed to investigational new drug (IND) and clinical trial stages.

Duties and Responsibilities:

• Required to evaluate bioactivity assays and recommend strategies and experiments to optimize and/or validate the assays for use in a medicinal chemistry campaign.
• Assist in the establishment of milestones related to assay optimization or validation.
• Provide guidance on the design and interpretation of commonly used in vivo assays, such as cognitive and behavioral tests.
• Serve as the assay development expert in order to identify potential developmental challenges and suggest strategies to address these challenges on realistic timelines.
• Advise, strategically plan, and manage programs to facilitate lead optimization, IND enabling, and clinical studies.
• Serve as a resource to lead development team members for assay requirements, and logistics to conduct drug development activities for small molecule compounds from the preclinical stage through to the initial clinical stage.
• Serve as a resource to lead development team members for assay requirements, and logistics to conduct drug development activities for small molecule compounds from the preclinical stage through to the initial clinical stage.
• Accompany NIH staff or visit, at NIH program staff request, Contract Research Organizations [CRO] under contract to the NIH (e.g. NIH Blueprint Neurotherapeutics Network (BPN) or the NIH Helping to End Addiction Long Term (HEAL)). Assist NIH staff in inspecting facilities and discuss appropriateness of CRO proposed methodology. Submit trip reports to BPN and HEAL program staff.
• Collaborate on the design of investigative studies in support of development compounds.
• Work in a virtual, cross-functional team environment and manage competing priorities.
• All other duties as assigned.

Minimum Requirements:

• Advanced degree in scientific discipline - required.
• 15+ years of experience in assay development in pharmaceutical industry.
• 15+ years of experience in application automated technologies and robotics relevant to pharmaceutical assays.
• Experience with drug discovery and development for nervous system conditions - required.
• Experience working with multi-disciplinary teams at a senior level in the biopharmaceutical industry, especially teams with members from outside organizations and members at various management levels.
• Broad experience across the entire drug discovery and development process is especially desired.
• Experience in pain therapeutics, small molecule and biologics therapeutics for pain relief will be considered a plus.
• Experience managing or being a senior leader in drug discovery and development projects in the biopharmaceutical industry.
• Experience in team leadership, consulting, or service on strategic and advisory boards will be considered.
• Must have strong interpersonal skills, an attention to detail, excellent organizational, writing, communication, presentation and documentation skills as well as computer and software literacy.

Apply online at our website: https://kikiktagruk.applicantpool.com/

Disclaimer:

This is not to be an exclusive list of all responsibilities, duties, and skills required of the person in this job. ?KIC is an Equal Opportunity Employer as to all protected groups, including protected veterans and individuals with disabilities.

Pursuant to The Alaska Native Claims Settlement Act 43 U.S.C. Sec. 1601 et seq., and federal contractual requirements, Kikiktagruk Inupiat Corporation, may legally grant certain preference in employment opportunities to KIC Shareholders, and their Descendants.

Successful candidates must adhere to KIC's Drug and Alcohol policy/testing requirements and may be required to pass a background and/or Motor Vehicle Records check.

The salary range for this position is based on several factors, including relevant experience, education, skills, and current market conditions.??

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